The mesh is the computer

The article

The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle

announces the discovery of a new structure in the cell: the mesh.

From the abstract:

Kinetochore fibers (K-fibers) of the mitotic spindle are force-generating units that power chromosome movement during mitosis. K-fibers are composed of many microtubules that are held together throughout their length.
Here, we show, using 3D electron microscopy, that K-fiber microtubules (MTs) are connected by a network of MT connectors. We term this network ‘the mesh’.
The K-fiber mesh is made of linked multipolar connectors. Each connector has up to four struts, so that a single connector can link up to four MTs.  […]
Optimal stabilization of K-fibers by the mesh is required for normal progression through mitosis.
We propose that the mesh stabilizes K-fibers by pulling MTs together and thereby maintaining the integrity of the fiber. “

My speculation is that the mesh has not only the role of a scaffold for the microtubule structure.

Together with the microtubules and with some other (yet undiscovered or, on the contrary, very well known) parts, this is the computer.

 

F1.large

DNA, which fascinates us, is more like a memory device.

But the computation may be as in  chemlambda. The dynamical reorganization of the mesh-microtubule-other proteins structure is very much resembling to a chemlambda molecule (or even to a chemlambda quine.

20_20_hyb

 

Mentioned this here, because there is an evocative image

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